Accupril
Definition
Accupril is an angiotensin-converting enzyme (ACE) inhibitor used primarily to treat high blood pressure and heart failure. It helps relax blood vessels, making it easier for the heart to pump blood.
5 Must Know Facts For Your Next Test
- Accupril's generic name is Quinapril.
- It works by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor.
- Common side effects include cough, dizziness, and headache.
- Patients with renal impairment may require dose adjustments when taking Accupril.
- Concurrent use with potassium-sparing diuretics can increase the risk of hyperkalemia.
Review Questions
- What is the mechanism of action of Accupril?
- What are some common side effects associated with Accupril?
- Why might dose adjustments be necessary for patients with renal impairment taking Accupril?
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Related terms
Angiotensin II: A peptide hormone that causes blood vessels to constrict, increasing blood pressure.
Hyperkalemia: A condition characterized by elevated levels of potassium in the blood, which can be a side effect of ACE inhibitors.
Renin-Angiotensin-Aldosterone System (RAAS): A hormone system that regulates blood pressure and fluid balance in the body.
