Abuse deterrence refers to the formulation strategies used in drug development to reduce the potential for misuse and abuse of medications, particularly opioids. These strategies can include physical and chemical barriers, agonist/antagonist combinations, aversion techniques, and prodrug approaches.
Opioid Antagonists: Drugs that block opioid receptors and reverse or prevent opioid effects.
Naloxone: A medication used to rapidly reverse opioid overdose.
Methadone: A long-acting opioid used for pain management and as part of addiction treatment programs.