Reticulocyte

Definition

Reticulocytes are immature red blood cells (RBCs) that have recently been released from the bone marrow into the bloodstream. They play a crucial role in assessing bone marrow activity and overall hematologic health.

5 Must Know Facts For Your Next Test

1. Reticulocyte count is a key indicator of erythropoietic activity and can help diagnose types of anemia.
2. A high reticulocyte count often indicates increased RBC production, possibly due to hemorrhage or hemolysis.
3. A low reticulocyte count may suggest bone marrow failure or deficiencies in necessary nutrients like iron, vitamin B12, or folate.
4. Reticulocytes still contain ribosomal RNA, which distinguishes them from mature red blood cells under a microscope.
5. Nutrition impacts reticulocyte levels; adequate intake of iron, vitamin B12, and folate is essential for proper RBC production.

Review Questions

• What does a high reticulocyte count indicate about erythropoietic activity?
• Why might a low reticulocyte count be observed in patients with nutritional deficiencies?
• How can nutrition influence reticulocyte levels in the bloodstream?

Related terms

Erythropoiesis: The process of producing new red blood cells within the bone marrow.

Anemia: A condition characterized by a deficiency of red blood cells or hemoglobin, leading to fatigue and weakness.

Hematocrit: The proportion of blood volume that is occupied by red blood cells, used as an indicator of overall blood health.