Renin-angiotensin-aldosterone system (RAAS)

Definition

The Renin-angiotensin-aldosterone system (RAAS) is a hormone system that regulates blood pressure and fluid balance. Activation of RAAS leads to sodium retention, potassium excretion, and water retention, impacting overall cardiovascular health and endocrine wellness.

5 Must Know Facts For Your Next Test

1. RAAS is activated when there is a drop in blood pressure or blood volume.
2. Renin, produced by the kidneys, initiates the cascade by converting angiotensinogen to angiotensin I.
3. Angiotensin I is converted to angiotensin II by the enzyme ACE (Angiotensin-Converting Enzyme).
4. Angiotensin II stimulates the release of aldosterone from the adrenal glands, which increases sodium reabsorption in the kidneys.
5. Nutritional strategies influencing RAAS include managing sodium intake and ensuring adequate potassium levels.

Review Questions

• What triggers the activation of the RAAS?
• How does angiotensin II affect aldosterone release?
• Why is managing sodium intake important in relation to RAAS?

Related terms

Aldosterone: A hormone released from the adrenal glands that increases sodium reabsorption in the kidneys.

Angiotensin II: A potent vasoconstrictor that also stimulates aldosterone release and increases blood pressure.

ACE Inhibitors: Medications that inhibit Angiotensin-Converting Enzyme (ACE), used to lower blood pressure.