Nutrition for Nurses

study guides for every class

that actually explain what's on your next test

Proton pump inhibitors

from class:

Nutrition for Nurses

Definition

Proton pump inhibitors (PPIs) are a class of medications that reduce stomach acid production by blocking the enzyme in the stomach wall responsible for acid secretion. They are commonly used to treat conditions like gastroesophageal reflux disease (GERD), ulcers, and other digestive disorders.

congrats on reading the definition of Proton pump inhibitors. now let's actually learn it.

ok, let's learn stuff

5 Must Know Facts For Your Next Test

  1. PPIs can lead to nutrient malabsorption, particularly Vitamin B12 and magnesium, which is crucial for neurological health.
  2. Long-term use of PPIs has been associated with an increased risk of fractures due to impaired calcium absorption.
  3. Patients on PPIs may experience altered gut microbiota, impacting overall gut health and potentially leading to infections like Clostridium difficile.
  4. PPIs are often prescribed alongside NSAIDs (non-steroidal anti-inflammatory drugs) to prevent gastric ulcers in patients requiring long-term NSAID therapy.
  5. Regular monitoring and periodic reevaluation of PPI therapy are recommended to minimize potential adverse effects, especially in elderly patients.

Review Questions

  • What essential nutrients' absorption can be affected by prolonged PPI use?
  • Why might long-term PPI use increase the risk of bone fractures?
  • How do PPIs impact gut microbiota and what potential infections can arise from this alteration?
© 2024 Fiveable Inc. All rights reserved.
AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.
Glossary
Guides