Penicillamine

Definition

Penicillamine is a chelating agent used primarily to treat Wilson's disease and rheumatoid arthritis. It works by binding to metals like copper, aiding in their excretion from the body.

5 Must Know Facts For Your Next Test

1. Penicillamine is often prescribed for patients with neurologic symptoms due to Wilson's disease.
2. It can cause severe side effects including gastrointestinal issues, skin rash, and changes in blood cell counts.
3. Long-term use of penicillamine requires regular monitoring of liver function and blood counts.
4. Penicillamine may interact with other medications and supplements, necessitating careful management of nutrition.
5. A common nutritional concern with penicillamine therapy is its potential to deplete essential nutrients such as zinc and vitamin B6.

Review Questions

• What neurological condition is penicillamine most commonly prescribed for?
• What are some severe side effects that nurses should monitor for in patients taking penicillamine?
• How does penicillamine impact nutritional management, particularly regarding essential nutrients?

Related terms

Wilson's Disease: An inherited disorder causing excessive accumulation of copper in the liver, brain, and other vital organs.

Chelating Agent: A substance that binds to metals in the body, facilitating their excretion.

Rheumatoid Arthritis:

An autoimmune disorder causing inflammation of the joints leading to pain and deformity.