NSAIDS

Definition

NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) are a class of medications used to reduce inflammation, alleviate pain, and lower fevers. They are commonly used in managing conditions like arthritis and musculoskeletal injuries.

5 Must Know Facts For Your Next Test

1. NSAIDs inhibit the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins that cause inflammation and pain.
2. Common examples include ibuprofen, naproxen, and aspirin.
3. Long-term use of NSAIDs can lead to gastrointestinal issues such as ulcers and bleeding.
4. They can negatively impact kidney function, especially in individuals with pre-existing kidney conditions.
5. NSAIDs may interfere with bone healing processes, potentially delaying recovery from fractures or surgeries.

Review Questions

• What enzyme do NSAIDs inhibit to reduce inflammation?
• Name two common NSAIDs used in clinical practice.
• What are some potential side effects of long-term NSAID use?

Related terms

Cyclooxygenase (COX): An enzyme that plays a key role in the formation of pro-inflammatory chemicals called prostaglandins.

Prostaglandins:

Lipid compounds that have various hormone-like effects, including promoting inflammation, pain, and fever.

Arthritis:

A condition causing inflammation of the joints, often treated with NSAIDs for pain relief.