Irritability

Definition

Irritability is a state of heightened sensitivity and responsiveness to stimuli, often resulting in frustration or anger. It can be influenced by various factors, including nutritional deficiencies that impact hematologic health.

5 Must Know Facts For Your Next Test

1. Irritability can be an early sign of iron deficiency anemia, which affects red blood cell production.
2. Vitamin B12 deficiency can lead to irritability due to its role in neurological function and red blood cell formation.
3. Inadequate intake of folate may contribute to irritability by affecting DNA synthesis and repair in blood cells.
4. Electrolyte imbalances, particularly low magnesium levels, are linked to increased irritability and mood disturbances.
5. Chronic inflammation caused by poor diet can exacerbate irritability by affecting cytokine levels and brain function.

Review Questions

• How does iron deficiency anemia contribute to irritability?
• What role does Vitamin B12 play in preventing irritability?
• Why might low magnesium levels increase irritability?

Related terms

Anemia:

A condition characterized by a deficiency of red blood cells or hemoglobin, leading to fatigue and weakness.

Folate:

A B-vitamin essential for DNA synthesis and repair, crucial for red blood cell production.

Cytokines: Proteins involved in cell signaling that can influence inflammation and immune responses.