Insulin resistance

Definition

Insulin resistance is a condition where cells in the body become less responsive to the hormone insulin, leading to impaired glucose uptake and elevated blood sugar levels. This condition is a key factor in the development of type 2 diabetes and metabolic syndrome.

5 Must Know Facts For Your Next Test

1. Insulin resistance often precedes the development of type 2 diabetes and can be exacerbated by poor dietary habits.
2. High levels of visceral fat are strongly associated with increased insulin resistance.
3. Physical activity and weight loss can improve insulin sensitivity and help manage or prevent insulin resistance.
4. A diet high in refined sugars and low in fiber is linked to increased risk of developing insulin resistance.
5. Chronic inflammation is both a cause and consequence of insulin resistance, influencing endocrine function.

Review Questions

• What are the primary dietary factors that contribute to the development of insulin resistance?
• How does physical activity impact insulin sensitivity?
• What role does chronic inflammation play in insulin resistance?

Related terms

Type_2_Diabetes: A chronic condition characterized by high blood sugar levels due to insulin resistance or inadequate insulin production.

Metabolic_Syndrome: A cluster of conditions including high blood pressure, high blood sugar, excess abdominal fat, and abnormal cholesterol levels that increase the risk for heart disease and diabetes.

Visceral_Fat: Fat stored within the abdominal cavity around internal organs, which is closely linked to increased risk for metabolic diseases.