Imipramine

Definition

Imipramine is a tricyclic antidepressant used primarily to treat depression and certain types of anxiety. It is also prescribed for neuropathic pain and sometimes for nocturnal enuresis in children.

5 Must Know Facts For Your Next Test

1. Imipramine affects neurotransmitters in the brain, particularly serotonin and norepinephrine.
2. It can cause side effects such as dry mouth, constipation, urinary retention, and blurred vision due to its anticholinergic properties.
3. Patients on imipramine should avoid alcohol and other central nervous system depressants to prevent excessive sedation.
4. Nutrition considerations include monitoring for weight gain, which can be a side effect of imipramine.
5. Regular blood pressure monitoring is necessary as imipramine can cause orthostatic hypotension.

Review Questions

• What neurotransmitters are primarily affected by imipramine?
• List at least two common side effects associated with imipramine use.
• Why is it important to monitor weight and blood pressure in patients taking imipramine?

Related terms

Serotonin: A neurotransmitter that contributes to feelings of well-being and happiness.

Norepinephrine: A neurotransmitter involved in arousal and regulation of blood pressure.

Tricyclic Antidepressants: A class of medications used to treat depression by affecting neurotransmitter levels in the brain.