Histamine

Definition

Histamine is a biogenic amine involved in local immune responses and regulating physiological functions in the gut. It also acts as a neurotransmitter for the brain, spinal cord, and uterus.

5 Must Know Facts For Your Next Test

1. Histamine is released by mast cells and basophils during allergic reactions and inflammation.
2. It can cause bronchoconstriction, increasing airway resistance and impacting pulmonary wellness.
3. Certain foods can trigger histamine release or contain high levels of histamine, which may exacerbate respiratory symptoms.
4. Antihistamines are commonly used to manage symptoms related to histamine release such as sneezing, itching, and asthma exacerbations.
5. A diet low in histamine can be beneficial for individuals with histamine intolerance or certain pulmonary conditions.

Review Questions

• What role does histamine play in allergic reactions?
• How can histamine impact pulmonary wellness?
• Why might a low-histamine diet be recommended for some patients?

Related terms

Mast Cells: Immune cells that store and release histamine during inflammatory and allergic responses.

Antihistamines: Medications that block the effects of histamine, commonly used to relieve allergy symptoms.

Bronchoconstriction:

The narrowing of airways in the lungs due to tightening of surrounding smooth muscle, often influenced by histamine.