H2 receptor antagonists

Definition

H2 receptor antagonists are a class of medications that reduce stomach acid production by blocking histamine receptors in the stomach lining. They are commonly used to treat conditions like ulcers, gastroesophageal reflux disease (GERD), and other acid-related disorders.

5 Must Know Facts For Your Next Test

1. H2 receptor antagonists can interfere with the absorption of certain nutrients, such as vitamin B12 and iron, which are essential for hematologic health.
2. These medications can be prescribed to manage upper gastrointestinal symptoms in patients with hematologic malignancies undergoing chemotherapy.
3. Long-term use of H2 receptor antagonists has been linked to an increased risk of anemia due to impaired nutrient absorption.
4. Nurses should monitor hematologic parameters in patients on prolonged H2 receptor antagonist therapy to detect potential deficiencies early.
5. Common H2 receptor antagonists include ranitidine, famotidine, cimetidine, and nizatidine.

Review Questions

• How do H2 receptor antagonists affect the absorption of vitamin B12 and iron?
• What is a common side effect of long-term use of H2 receptor antagonists related to hematologic health?
• Name two conditions that H2 receptor antagonists are commonly used to treat.

Related terms

Proton Pump Inhibitors (PPIs): Medications that reduce stomach acid production by blocking the enzyme responsible for acid secretion.

Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach acid frequently flows back into the esophagus, causing irritation.

Anemia: A condition characterized by a deficiency of red blood cells or hemoglobin, leading to fatigue and weakness.