Basophils

Definition

Basophils are a type of white blood cell that play a role in immune response by releasing histamine and other chemicals during allergic reactions. They are the least common type of granulocyte, making up less than 1% of circulating white blood cells.

5 Must Know Facts For Your Next Test

1. Basophils contain granules rich in histamine and heparin, which contribute to inflammatory responses.
2. They are involved in the body's defense mechanisms against parasites and bacteria.
3. Elevated basophil levels can indicate allergic reactions or chronic inflammation.
4. Nutritional deficiencies, particularly in vitamins like B12, can affect basophil counts and function.
5. Proper nutrition is essential for maintaining a balanced immune response, which includes the activity of basophils.

Review Questions

• What role do basophils play in allergic reactions?
• How can nutritional deficiencies impact basophil function?
• Why is it important to monitor basophil levels in patients with chronic inflammation?

Related terms

Histamine: A compound released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries.

Granulocyte: A type of white blood cell filled with microscopic granules containing enzymes that digest microorganisms.

Heparin: An anticoagulant found in the body that prevents blood clotting.