Azathioprine

Definition

Azathioprine is an immunosuppressive medication commonly used to treat autoimmune diseases and prevent organ rejection after transplants. It works by inhibiting the proliferation of certain cells in the immune system, reducing inflammation and immune responses.

5 Must Know Facts For Your Next Test

1. Azathioprine is often prescribed for inflammatory bowel diseases like Crohn's disease and ulcerative colitis.
2. Patients on azathioprine may require regular blood tests to monitor liver function and blood cell counts due to potential side effects.
3. Dietary considerations include avoiding foods that may interact with the drug or exacerbate gastrointestinal issues, such as high-fat or spicy foods.
4. Vitamin supplementation, particularly folic acid, may be recommended since azathioprine can affect nutrient absorption.
5. Hydration is crucial for patients taking azathioprine to help prevent kidney complications.

Review Questions

• What are common gastrointestinal conditions treated with azathioprine?
• Why are regular blood tests necessary for patients taking azathioprine?
• How can nutrition play a role in managing side effects of azathioprine?

Related terms

Immunosuppressants: Drugs that inhibit or prevent activity of the immune system to reduce inflammation or prevent organ rejection.

Crohn's Disease:

A chronic inflammatory condition of the gastrointestinal tract that can cause severe digestive issues.

Folic Acid:

A type of B vitamin important for cell division and growth, often supplemented during azathioprine treatment due to its impact on nutrient absorption.