Atrophic gastritis

Definition

Atrophic gastritis is a chronic inflammation of the stomach lining leading to the loss of gastric glandular cells. This condition can result in reduced production of stomach acid and intrinsic factor, affecting digestion and nutrient absorption.

5 Must Know Facts For Your Next Test

1. Atrophic gastritis can lead to vitamin B12 deficiency due to impaired absorption.
2. It is often caused by Helicobacter pylori infection or autoimmune disorders.
3. Symptoms may include abdominal pain, nausea, and a feeling of fullness after eating small amounts.
4. The condition increases the risk of developing gastric cancer.
5. Diagnosis is typically confirmed through endoscopy and biopsy of the stomach lining.

Review Questions

• What are the primary causes of atrophic gastritis?
• How does atrophic gastritis affect nutrient absorption?
• What diagnostic methods are used to confirm atrophic gastritis?

Related terms

Peptic Ulcer Disease: A condition where open sores develop on the inner lining of the stomach or duodenum.

Helicobacter Pylori: A type of bacteria that infects the stomach and is a common cause of ulcers.

Intrinsic Factor: A glycoprotein produced by parietal cells in the stomach necessary for vitamin B12 absorption.