All Subjects

Amyloids

Definition

Amyloids are abnormal protein aggregates that form fibrils and plaques in tissues. They are often implicated in various neurological disorders, affecting brain function and structure.

5 Must Know Facts For Your Next Test

  1. Amyloids are primarily associated with Alzheimer's disease, where they accumulate as beta-amyloid plaques.
  2. Nutritional factors such as antioxidants and omega-3 fatty acids may influence amyloid formation and aggregation.
  3. Amyloid deposits can disrupt cell-to-cell communication in the brain, leading to neurodegenerative conditions.
  4. Certain dietary patterns like the Mediterranean diet have been linked to reduced amyloid plaque formation.
  5. Research suggests that insulin resistance and type 2 diabetes may increase the risk of amyloid-related neurological diseases.

Review Questions

  • How do amyloids contribute to Alzheimer's disease?
  • What role do dietary antioxidants play in amyloid formation?
  • Which dietary pattern is associated with reduced amyloid plaque accumulation?

Related terms

Alzheimer's Disease: A neurodegenerative disorder characterized by progressive memory loss and cognitive decline due to amyloid plaques and tau tangles.

Beta-Amyloid: A peptide that aggregates to form plaques in the brains of individuals with Alzheimer's disease.

Neurodegeneration: The progressive loss of structure or function of neurons, often associated with disorders such as Alzheimer's and Parkinson's disease.



ยฉ 2024 Fiveable Inc. All rights reserved.
APยฎ and SATยฎ are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.

ยฉ 2024 Fiveable Inc. All rights reserved.

APยฎ and SATยฎ are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.