Akkermansia muciniphila

Definition

Akkermansia muciniphila is a beneficial bacterium found in the human gut, particularly known for its ability to degrade mucin. It plays a crucial role in maintaining gut barrier integrity and metabolic health.

5 Must Know Facts For Your Next Test

1. Akkermansia muciniphila is associated with improved gut barrier function and reduced inflammation.
2. It has been linked to better metabolic outcomes, such as lower body weight and improved insulin sensitivity.
3. Low levels of Akkermansia muciniphila are often found in individuals with obesity, type 2 diabetes, and inflammatory bowel disease.
4. Dietary interventions like prebiotics can help increase the abundance of Akkermansia muciniphila in the gut.
5. Research suggests that this bacterium may have potential as a probiotic for enhancing gastrointestinal health.

Review Questions

• How does Akkermansia muciniphila contribute to gut barrier integrity?
• What are some health conditions associated with low levels of Akkermansia muciniphila?
• Which types of dietary interventions can increase the abundance of Akkermansia muciniphila?

Related terms

Gut Microbiome:

The community of microorganisms living in the human digestive tract.

Prebiotics:

Non-digestible food ingredients that promote the growth of beneficial microorganisms in the intestines.

Probiotics:

Live bacteria and yeasts that are beneficial for digestive health when consumed.