Adult-onset obesity

Definition

Adult-onset obesity is the condition where individuals gain excessive weight after reaching adulthood, typically due to lifestyle factors. It can significantly affect neurological health through various metabolic and inflammatory pathways.

5 Must Know Facts For Your Next Test

1. Adult-onset obesity increases the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's.
2. Chronic inflammation associated with adult-onset obesity can lead to cognitive decline.
3. Obesity in adulthood is linked to reduced levels of brain-derived neurotrophic factor (BDNF), impacting neuronal health.
4. Excessive weight gain in adults can impair the blood-brain barrier, making the brain more vulnerable to toxins.
5. Lifestyle changes including diet and exercise are critical for managing adult-onset obesity and its neurological impacts.

Review Questions

• How does adult-onset obesity contribute to the risk of neurodegenerative diseases?
• What role does chronic inflammation play in cognitive decline associated with adult-onset obesity?
• Why are lifestyle changes important for managing the neurological impacts of adult-onset obesity?

Related terms

Neuroinflammation:

Inflammation of nervous tissue, often linked to neurodegenerative diseases and affected by metabolic conditions like obesity.

Brain-Derived Neurotrophic Factor (BDNF): A protein crucial for neuron survival and plasticity; its levels can be negatively affected by obesity.

Blood-Brain Barrier:

A selective barrier that protects the brain from harmful substances; its integrity can be compromised by obesity-related metabolic issues.