Adult-onset obesity is the condition where individuals gain excessive weight after reaching adulthood, typically due to lifestyle factors. It can significantly affect neurological health through various metabolic and inflammatory pathways.
Neuroinflammation: Inflammation of nervous tissue, often linked to neurodegenerative diseases and affected by metabolic conditions like obesity.
Brain-Derived Neurotrophic Factor (BDNF): A protein crucial for neuron survival and plasticity; its levels can be negatively affected by obesity.
Blood-Brain Barrier: A selective barrier that protects the brain from harmful substances; its integrity can be compromised by obesity-related metabolic issues.