🦠microbiology review

Tetanus toxoid (TT) vaccine

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Tetanus toxoid (TT) vaccine is an immunization used to prevent tetanus, a serious bacterial infection affecting the nervous system. It stimulates the body's immune response to produce antibodies against the toxin produced by Clostridium tetani.

5 Must Know Facts For Your Next Test

  1. Tetanus toxoid vaccine is essential in preventing tetanus, especially after injuries involving soil or rust-contaminated objects.
  2. The vaccine is typically administered as part of a combination vaccine, such as DTaP (Diphtheria, Tetanus, and Pertussis).
  3. Booster doses are recommended every 10 years to maintain immunity against tetanus.
  4. Tetanus can lead to severe muscle spasms and lockjaw, which can be fatal if untreated.
  5. The TT vaccine works by inducing active immunity through the production of antibodies specific to the tetanus toxin.

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