SsDNA

Definition

ssDNA stands for single-stranded DNA, which is a DNA molecule consisting of only one strand as opposed to the normal double-stranded structure. It plays crucial roles in viral replication and various molecular biology techniques.

5 Must Know Facts For Your Next Test

1. ssDNA viruses often rely on host cellular machinery to replicate their genomes.
2. Phages like M13 and ΦX174 are examples of ssDNA viruses that infect bacteria.
3. Replication of ssDNA involves the synthesis of a complementary strand to form double-stranded DNA (dsDNA).
4. ssDNA can be used in laboratory techniques such as PCR and sequencing.
5. Some human pathogens, like Parvovirus B19, have ssDNA genomes.

Review Questions

• What process converts ssDNA into a double-stranded form during viral replication?
• Name two examples of ssDNA viruses.
• How is ssDNA utilized in molecular biology techniques?

Related terms

dsDNA:

Double-stranded DNA consists of two complementary strands forming a helical structure.

PCR:

Polymerase Chain Reaction is a technique used to amplify specific regions of DNA.

Parvovirus B19:

A human pathogen with an ssDNA genome causing diseases such as erythema infectiosum.