Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
ssDNA stands for single-stranded DNA, which is a DNA molecule consisting of only one strand as opposed to the normal double-stranded structure. It plays crucial roles in viral replication and various molecular biology techniques.
5 Must Know Facts For Your Next Test
ssDNA viruses often rely on host cellular machinery to replicate their genomes.
Phages like M13 and ΦX174 are examples of ssDNA viruses that infect bacteria.
Replication of ssDNA involves the synthesis of a complementary strand to form double-stranded DNA (dsDNA).
ssDNA can be used in laboratory techniques such as PCR and sequencing.
Some human pathogens, like Parvovirus B19, have ssDNA genomes.