Solvaldi

Definition

Sovaldi is an antiviral medication used to treat hepatitis C virus (HCV) infection. It works by inhibiting the RNA polymerase enzyme, which is essential for viral replication.

5 Must Know Facts For Your Next Test

1. Sovaldi's generic name is sofosbuvir.
2. It specifically targets the NS5B polymerase of the hepatitis C virus.
3. Sovaldi must be used in combination with other antiviral medications and is not effective as monotherapy.
4. It has a high cure rate, often exceeding 90% when combined with other drugs like ribavirin or ledipasvir.
5. The drug was approved by the FDA in December 2013 and marked a significant advancement in HCV treatment.

Review Questions

Related terms

Ribavirin:

An antiviral drug often used in combination with Sovaldi to treat hepatitis C.

NS5B Polymerase: An RNA-dependent RNA polymerase targeted by Sovaldi to inhibit viral replication.

Ledipasvir: Another antiviral medication commonly combined with sofosbuvir for treating HCV.