🦠microbiology review

Small subunit

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The small subunit is a component of the ribosome that binds to mRNA and initiates translation. It plays a crucial role in decoding the mRNA sequence into a polypeptide chain.

5 Must Know Facts For Your Next Test

  1. The small subunit of the ribosome binds to the mRNA at the start codon (AUG).
  2. It is responsible for the correct positioning of the mRNA and tRNAs during translation.
  3. In prokaryotes, the small subunit is 30S, while in eukaryotes, it is 40S.
  4. The small subunit works with initiation factors to form the initiation complex.
  5. The accuracy of translation initiation largely depends on the proper functioning of the small subunit.

Review Questions

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