Risks

Definition

Risks in gene therapy refer to the potential adverse effects and uncertainties associated with the use of genetic techniques to treat diseases. They can include unintended genetic modifications, immune reactions, and ethical concerns.

5 Must Know Facts For Your Next Test

1. Risks of gene therapy can lead to insertional mutagenesis where the introduced gene disrupts normal genes.
2. Immune responses to viral vectors used in gene therapy can cause severe inflammatory reactions.
3. Off-target effects due to imprecise editing technologies may result in unintended genetic changes.
4. Ethical considerations include potential long-term impacts on future generations and consent issues.
5. Monitoring and regulatory frameworks are essential to mitigate risks and ensure patient safety.

Review Questions

Related terms

Viral Vectors:

Modified viruses used as delivery systems for therapeutic genes.

Insertional Mutagenesis:

A mutation caused by the insertion of new genetic material into a host genome.

Off-Target Effects:

Unintended modifications made by genome editing technologies at sites other than the intended target.