Polymicrobic infections

Definition

Polymicrobic infections are infections caused by multiple species of microorganisms simultaneously. These can include bacteria, viruses, fungi, or parasites and often present a complex challenge for treatment.

5 Must Know Facts For Your Next Test

1. Polymicrobic infections often require broad-spectrum or combination antimicrobial therapy to target all involved microorganisms.
2. These infections can complicate diagnosis and treatment due to the presence of multiple pathogens with different resistance patterns.
3. Biofilms are common in polymicrobic infections, making them more resistant to standard antimicrobial treatments.
4. Common sites for polymicrobic infections include wounds, respiratory tracts, and the gastrointestinal system.
5. Treatment strategies must consider potential drug interactions and synergistic effects among different antimicrobials.

Review Questions

• Why do polymicrobic infections often require combination antimicrobial therapy?
• What is a common complication associated with the treatment of polymicrobic infections?
• Name three common sites where polymicrobic infections can occur.

Related terms

Broad-Spectrum Antibiotics: Antibiotics that are effective against a wide range of both Gram-positive and Gram-negative bacteria.

Biofilm: A structured community of microbial cells enclosed in a self-produced polymeric matrix adherent to an inert or living surface.

Drug Synergism: The interaction between two drugs that results in a greater effect than when the drugs are used separately.