🦠microbiology review

Picornaviruses

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Picornaviruses are a family of small, non-enveloped RNA viruses that include notable pathogens such as poliovirus and rhinoviruses. They are known for their ability to cause a variety of diseases in humans, ranging from the common cold to more severe illnesses like hepatitis A.

5 Must Know Facts For Your Next Test

  1. Picornaviruses replicate rapidly within host cells by hijacking the host's machinery.
  2. These viruses have a positive-sense single-stranded RNA genome.
  3. The antiviral drug Pleconaril has been studied for its effectiveness against picornaviruses.
  4. Picornaviruses can be transmitted via fecal-oral routes or respiratory droplets depending on the specific virus.
  5. They have an icosahedral capsid that protects their genetic material.

Review Questions