Naphthoquinone

Definition

Naphthoquinone is an organic compound derived from naphthalene with a quinone structure. It is known for its role in various biological and pharmacological activities, including antimicrobial properties.

5 Must Know Facts For Your Next Test

1. Naphthoquinones are involved in the electron transport chain as they can undergo redox reactions.
2. They exhibit antimicrobial activity by interfering with microbial respiration and energy production.
3. Naphthoquinones have been studied for their potential use in treating infections caused by bacteria, fungi, and parasites.
4. Vitamin K, essential for blood clotting, is a type of naphthoquinone.
5. Resistance to naphthoquinone-based drugs is less common compared to other antibiotics.

Review Questions

• What role do naphthoquinones play in microbial respiration?
• How do naphthoquinones exert their antimicrobial effects?
• Why might resistance to naphthoquinone-based drugs be less common?

Related terms

Quinone: A class of organic compounds characterized by a fully conjugated cyclic dione structure.

Electron Transport Chain: A series of protein complexes that transfer electrons through a membrane to create a gradient used for ATP synthesis.

Antimicrobial Drug Resistance: The ability of microorganisms to withstand the effects of an antimicrobial agent that once could successfully treat the infection.