Mefloquine Definition - Microbiology Key Term

Definition

Mefloquine is an antimalarial drug used to prevent and treat malaria. It works by interfering with the growth of parasites in the red blood cells.

Mefloquine is effective against Plasmodium falciparum, the parasite responsible for most malaria-related deaths.
It is often used in regions where chloroquine-resistant malaria is prevalent.
Common side effects include dizziness, nausea, and vivid dreams or nightmares.
Mefloquine has a long half-life, which allows for weekly dosing when used as prophylaxis.
Resistance to mefloquine can arise due to mutations in the parasite’s genome, particularly in the pfmdr1 gene.

An antimalarial drug that targets the same parasites but has different resistance profiles.

The most dangerous species of Plasmodium causing severe forms of malaria.

The ability of microorganisms to withstand antimicrobial treatments such as antibiotics and antimalarials.