Lucanthone

Definition

Lucanthone is an antimicrobial drug primarily used to treat schistosomiasis, a parasitic infection. It works by inhibiting DNA synthesis and causing damage to the parasite's DNA.

5 Must Know Facts For Your Next Test

1. Lucanthone is effective against schistosome parasites, particularly Schistosoma haematobium.
2. The drug acts by intercalating into DNA and inhibiting topoisomerase II, leading to DNA damage.
3. Lucanthone is often administered orally in the form of tablets.
4. Common side effects include nausea, vomiting, and dizziness.
5. It has been largely replaced by praziquantel due to its higher efficacy and better safety profile.

Related terms

Schistosomiasis:

A parasitic disease caused by blood flukes known as schistosomes.

Topoisomerase II Inhibitor: A class of drugs that interfere with the enzyme topoisomerase II, involved in altering the supercoiling of DNA.

Praziquantel:

An antiparasitic medication that is highly effective against a variety of parasitic worms including those responsible for schistosomiasis.