🦠microbiology review

Hib vaccine

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The Hib vaccine protects against Haemophilus influenzae type b, a bacterium that can cause severe infections, including meningitis. It is crucial in preventing bacterial diseases that affect the nervous system.

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5 Must Know Facts For Your Next Test

  1. Hib vaccine is effective in reducing the incidence of bacterial meningitis caused by Haemophilus influenzae type b.
  2. Administered typically in infancy, it requires multiple doses for full immunization.
  3. Before the vaccine's introduction, Hib was a leading cause of bacterial meningitis in children under five.
  4. The vaccine contains purified polyribosylribitol phosphate (PRP) conjugated to a protein carrier to enhance immune response.
  5. Herd immunity from widespread vaccination helps protect unvaccinated individuals and those with compromised immune systems.

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