๐Ÿฆ microbiology review

key term - Cystic fibrosis

Definition

Cystic fibrosis (CF) is a genetic disorder that affects the respiratory and digestive systems, caused by mutations in the CFTR gene. It leads to thick, sticky mucus production, which obstructs airways and promotes bacterial infections.

5 Must Know Facts For Your Next Test

  1. CFTR gene mutations disrupt chloride ion transport, leading to thickened mucus.
  2. Pseudomonas aeruginosa is a common bacterial pathogen in CF patients' lungs.
  3. Sweat chloride test is a primary diagnostic tool for cystic fibrosis.
  4. Gene therapy is being explored as a treatment option for correcting defective CFTR genes in CF patients.
  5. CF patients often suffer from chronic respiratory infections due to impaired mucociliary clearance.

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