Cystic fibrosis (CF) is a genetic disorder that affects the respiratory and digestive systems, caused by mutations in the CFTR gene. It leads to thick, sticky mucus production, which obstructs airways and promotes bacterial infections.
5 Must Know Facts For Your Next Test
CFTR gene mutations disrupt chloride ion transport, leading to thickened mucus.
Pseudomonas aeruginosa is a common bacterial pathogen in CF patients' lungs.
Sweat chloride test is a primary diagnostic tool for cystic fibrosis.
Gene therapy is being explored as a treatment option for correcting defective CFTR genes in CF patients.
CF patients often suffer from chronic respiratory infections due to impaired mucociliary clearance.
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Related terms
CFTR Gene: A gene that codes for a protein involved in chloride ion transport; mutations cause cystic fibrosis.
Pseudomonas Aeruginosa: A bacterium frequently causing chronic respiratory infections in cystic fibrosis patients.