Clindamycin

Definition

Clindamycin is an antibiotic used to treat a variety of bacterial infections. It works by inhibiting protein synthesis in bacteria, making it effective against anaerobic bacteria and certain protozoa.

5 Must Know Facts For Your Next Test

1. Clindamycin is particularly effective against Gram-positive cocci and anaerobic bacteria.
2. It is commonly used for skin and soft tissue infections, including those caused by MRSA (Methicillin-resistant Staphylococcus aureus).
3. Clindamycin can be administered orally, topically, or intravenously depending on the infection severity.
4. A common side effect of clindamycin is Clostridioides difficile-associated diarrhea, which can lead to severe colitis.
5. The drug's mechanism involves binding to the 50S ribosomal subunit, preventing bacterial protein synthesis.

Review Questions

Related terms

Ribosome:

A cellular structure that facilitates protein synthesis.

MRSA:

Methicillin-resistant Staphylococcus aureus, a type of staph bacteria resistant to many antibiotics.

Anaerobic Bacteria: Bacteria that do not require oxygen for growth and may even die in its presence.