Benznidazole

Definition

Benznidazole is an antiprotozoal medication primarily used to treat Chagas disease, caused by the parasite Trypanosoma cruzi. It interferes with the DNA synthesis of the parasite, leading to its death.

5 Must Know Facts For Your Next Test

1. Benznidazole is one of the two drugs recommended by the World Health Organization (WHO) for treating Chagas disease.
2. The medication is most effective when administered during the acute phase of Chagas disease.
3. Common side effects include rash, gastrointestinal discomfort, and peripheral neuropathy.
4. Benznidazole has been shown to reduce parasitemia and delay or prevent the onset of chronic complications associated with Chagas disease.
5. It is typically given as a course lasting between 60 to 90 days.

Review Questions

Related terms

Trypanosoma cruzi:

The parasitic protozoan that causes Chagas disease.

Nifurtimox:

Another antiprotozoal drug used to treat Chagas disease.

Chronic Chagas Disease: The long-term phase of Chagas infection which can lead to serious cardiac and digestive system complications.