Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Benzathine benzylpenicillin is a long-acting antibiotic used to treat bacterial infections caused by penicillin-sensitive microorganisms. It is commonly employed in the treatment and prevention of rheumatic fever and syphilis.
5 Must Know Facts For Your Next Test
Benzathine benzylpenicillin is administered via intramuscular injection, ensuring prolonged drug release.
It is particularly effective against Streptococcus pyogenes, the bacterium responsible for causing rheumatic fever.
This antibiotic is indicated for use in prophylactic treatment to prevent recurrent episodes of rheumatic fever.
It can be used to treat early-stage syphilis caused by the bacterium Treponema pallidum.
Benzathine benzylpenicillin has a long half-life due to its slow absorption, allowing for less frequent dosing compared to other penicillins.