Amputation

Definition

Amputation is the surgical removal of a limb or extremity, often necessary due to severe infection or injury. In microbiology, it can be a critical intervention in preventing the spread of bacterial infections within the circulatory and lymphatic systems.

5 Must Know Facts For Your Next Test

1. Amputation may be necessary to stop the spread of severe bacterial infections like necrotizing fasciitis.
2. Bacterial infections such as Clostridium perfringens can lead to gas gangrene, necessitating amputation.
3. Systemic infections like sepsis can sometimes result in tissue death requiring amputation to save a patient's life.
4. Proper wound care and early antibiotic treatment are crucial in preventing conditions that might lead to amputation.
5. Infections leading to amputation are often associated with compromised blood flow and immune response.

Review Questions

Related terms

Necrotizing Fasciitis:

A severe bacterial infection causing tissue death; may require amputation.

Sepsis:

A life-threatening condition caused by the body's response to an infection, potentially leading to tissue damage.

Gangrene: The death of body tissue due to lack of blood flow or severe bacterial infection; may necessitate amputation.