Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
American trypanosomiasis, also known as Chagas disease, is a parasitic infection caused by the protozoan Trypanosoma cruzi. It primarily affects the cardiovascular and lymphatic systems.
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The parasite Trypanosoma cruzi is transmitted to humans through the feces of triatomine bugs, commonly known as 'kissing bugs.'
Chagas disease has two phases: an acute phase with mild or no symptoms and a chronic phase which can cause severe cardiac and digestive issues.
Diagnosis is typically made through blood tests that identify T. cruzi or its antibodies.
Nifurtimox and benznidazole are the main drugs used for treatment, particularly effective during the acute phase.
Preventive measures include improving housing conditions to avoid contact with triatomine bugs and using insecticides.