Log p, or logarithm of the partition coefficient (P), is a measure of the lipophilicity of a compound, indicating how well it partitions between an organic solvent (usually octanol) and water. A higher log p value suggests greater hydrophobicity, which often influences drug absorption, distribution, metabolism, and excretion (ADME) properties. Understanding log p helps in predicting the behavior of drugs within biological systems and their potential effectiveness.
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