The TATA box is a conserved DNA sequence found in the promoter region of many eukaryotic genes, typically located about 25 to 35 base pairs upstream of the transcription start site. This sequence plays a crucial role in the initiation of transcription by serving as a binding site for transcription factors and RNA polymerase II, helping to accurately position the transcription machinery at the start of gene expression. The presence of the TATA box is important for the proper regulation and expression of genes, making it a key feature in gene structure and organization.
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