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Mature ovum

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Developmental Biology

Definition

A mature ovum, also known as an oocyte, is the female gamete that is fully developed and ready for fertilization by a sperm cell. This cell undergoes significant changes during oogenesis, which prepares it for potential fertilization, including completing meiosis and acquiring necessary cellular components to support early embryonic development.

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5 Must Know Facts For Your Next Test

  1. The maturation of an ovum is part of the ovarian cycle and typically occurs once per menstrual cycle in humans.
  2. A mature ovum has completed meiosis I and is arrested in meiosis II until fertilization occurs.
  3. Once released during ovulation, the mature ovum has a lifespan of about 12 to 24 hours to be fertilized before it degenerates.
  4. The cytoplasm of a mature ovum is rich in nutrients and organelles, which are essential for supporting early stages of embryonic development after fertilization.
  5. Mature ova are produced in small numbers compared to sperm, with females typically releasing one ovum per cycle from puberty until menopause.

Review Questions

  • What are the key steps involved in oogenesis that lead to the formation of a mature ovum?
    • Oogenesis begins with the proliferation of oogonia, which differentiate into primary oocytes that enter meiosis but are arrested in prophase I. During each menstrual cycle, one primary oocyte resumes meiosis, completing meiosis I to form a secondary oocyte and a polar body. The secondary oocyte then enters meiosis II but is arrested at metaphase until fertilization occurs. This entire process is regulated by hormonal signals and results in the production of a mature ovum ready for potential fertilization.
  • How does the structure and composition of a mature ovum support its function in reproduction?
    • The mature ovum's structure is designed for successful fertilization and early development. It possesses a large cytoplasm filled with nutrients, organelles, and genetic material, ensuring it has all the necessary components to support the zygote post-fertilization. The zona pellucida, a glycoprotein layer surrounding the ovum, plays a vital role in protecting the egg and facilitating sperm binding during fertilization. Additionally, the presence of cortical granules helps prevent polyspermy once a sperm successfully fertilizes the ovum.
  • Evaluate the implications of aging on oogenesis and the quality of mature ova produced by females.
    • As females age, there is a decline in both the quantity and quality of ova produced due to factors such as decreased hormonal levels and increased chromosomal abnormalities. Older women may experience diminished ovarian reserve, leading to fewer available mature ova during each cycle. The quality of these ova can affect fertility rates and increase risks of genetic disorders in offspring. This decline emphasizes the importance of understanding reproductive aging in relation to family planning and assisted reproductive technologies.

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