Synaptic cleft

Definition

The synaptic cleft is the small gap between two neurons where neurotransmitters are released to transmit signals. It is crucial for neuronal communication and signal propagation in the nervous system.

5 Must Know Facts For Your Next Test

1. The synaptic cleft measures about 20-40 nanometers in width.
2. Neurotransmitters are released from the presynaptic neuron into the synaptic cleft.
3. Receptors on the postsynaptic neuron bind to neurotransmitters to propagate the signal.
4. Enzymes within the synaptic cleft can break down neurotransmitters to terminate the signal.
5. Synaptic vesicles in the presynaptic neuron contain and release neurotransmitters during synapse.

Review Questions

• What role do neurotransmitters play in the synaptic cleft?
• How wide is the typical synaptic cleft?
• What mechanisms exist in the synaptic cleft to terminate a neural signal?

Related terms

Neuron: A nerve cell that transmits electrical impulses.

Neurotransmitter: Chemical substances that transmit signals across a synapse.

Synapse: The junction between two neurons where communication occurs.