Transcription factors are proteins that help regulate the transcription of genes by binding to specific DNA sequences. They play a critical role in turning genes on or off in response to various cellular signals.
5 Must Know Facts For Your Next Test
Transcription factors can act as activators or repressors of gene expression.
They often bind to promoter or enhancer regions of DNA to influence RNA polymerase activity.
Many transcription factors require cofactors or other regulatory proteins to function properly.
Mutations in transcription factor genes can lead to diseases, including cancer and developmental disorders.
Epigenetic modifications such as methylation can affect the binding affinity of transcription factors.