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Thyroxine

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

Thyroxine, also known as T4, is a hormone produced by the thyroid gland that plays a crucial role in metabolism and growth. It regulates the rate of energy use and affects nearly every physiological process in the body, including body temperature and heart rate.

5 Must Know Facts For Your Next Test

  1. Thyroxine is synthesized from iodine and tyrosine within the thyroid gland.
  2. It is converted into triiodothyronine (T3), which is more potent and active in influencing metabolic activities.
  3. Thyroxine levels are regulated by thyroid-stimulating hormone (TSH) from the pituitary gland.
  4. A deficiency in thyroxine can lead to hypothyroidism, characterized by fatigue, weight gain, and depression.
  5. Excessive thyroxine production causes hyperthyroidism, which can result in symptoms like increased heart rate, anxiety, and weight loss.

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