Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Telophase is the final stage of mitosis, where two daughter nuclei form in a cell. Chromosomes decondense and the nuclear envelope reappears around each set of chromosomes.
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During telophase, the chromosomes that were tightly coiled and visible begin to uncoil and return to their less condensed state.
The nuclear envelopes reform around each set of separated sister chromatids now called daughter chromosomes.
Telophase is often concurrent with cytokinesis, which divides the cytoplasm of the parental cell into two daughter cells.
The mitotic spindle breaks down during this phase, allowing the nucleus to re-establish its structure.
Nucleoli reappear within the newly formed nuclei as telophase progresses.