Spontaneous mutations

Definition

Spontaneous mutations are changes in DNA sequence that occur naturally without any external influence. These mutations arise during normal cellular processes such as DNA replication and repair.

5 Must Know Facts For Your Next Test

1. Spontaneous mutations can result from errors during DNA replication.
2. They can also occur due to chemical changes in DNA, like deamination or depurination.
3. These mutations are usually rare events but can accumulate over time.
4. Spontaneous mutations can lead to genetic diversity within populations.
5. They may be corrected by various DNA repair mechanisms, such as base excision repair.

Review Questions

Related terms

DNA Replication: The process by which a cell duplicates its DNA before cell division.

Base Excision Repair: A cellular mechanism that repairs damaged DNA throughout the cell cycle.

Genetic Diversity: The total number of genetic characteristics in the genetic makeup of a species, contributing to variations within a population.