Sequence mapping

Definition

Sequence mapping is the process of determining the specific locations of genes and other significant sequences within a genome. It involves creating a detailed blueprint that shows where each gene or sequence is situated on a chromosome.

5 Must Know Facts For Your Next Test

1. Sequence mapping is crucial for identifying the exact position of genes associated with diseases.
2. There are different types of maps, including genetic maps and physical maps, each providing varying levels of detail.
3. Technologies like Next-Generation Sequencing (NGS) have significantly advanced the accuracy and speed of sequence mapping.
4. Sequence mapping can be used to compare genomes from different species to understand evolutionary relationships.
5. Errors in sequence mapping can lead to incorrect conclusions about gene function or location.

Review Questions

• What is the primary purpose of sequence mapping in genomics?
• How has Next-Generation Sequencing impacted the field of sequence mapping?
• Can you name two types of maps used in sequence mapping and their differences?

Related terms

Genetic Mapping: A type of genome mapping that estimates the relative positions of genes based on genetic recombination frequencies.

Physical Mapping: A method that provides the actual physical distance between genetic markers or genes on a chromosome, often measured in base pairs.

Next-Generation Sequencing (NGS): Advanced high-throughput sequencing technology that allows rapid sequencing and analysis of large segments of DNA.