Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
The sarcolemma is the cell membrane of a muscle fiber (muscle cell). It plays a crucial role in conducting electrical impulses necessary for muscle contraction.
5 Must Know Facts For Your Next Test
The sarcolemma surrounds each muscle fiber and is involved in transmitting action potentials.
It contains specialized proteins that help maintain the integrity and function of the muscle cell.
The sarcolemma features invaginations called T-tubules that facilitate the transmission of electrical signals into the muscle cell.
Damage to the sarcolemma can lead to muscular diseases such as muscular dystrophy.
It works closely with the endomysium, a type of connective tissue, to support and protect muscle fibers.