Rhodopsin is a light-sensitive receptor protein found in the rod cells of the retina. It plays a critical role in converting light into electrical signals that can be interpreted by the brain.
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Rhodopsin consists of opsin and retinal, a derivative of vitamin A.
It is responsible for the initial step in the perception of light, particularly in low-light conditions.
When rhodopsin absorbs light, it undergoes a conformational change called photobleaching.
The regeneration of rhodopsin from its bleached form requires enzymatic reactions involving retinal and opsin.
Mutations in the rhodopsin gene can lead to retinal diseases such as retinitis pigmentosa.
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Related terms
Opsin: The protein component of rhodopsin that binds to retinal.
Retinal: A derivative of vitamin A that acts as a chromophore within rhodopsin.
Rod Cells: Photoreceptor cells in the retina responsible for vision at low light levels.