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Proteome

Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025

Definition

The proteome is the entire set of proteins expressed by an organism, cell, or tissue at a certain time. It represents the functional output of the genome and can vary with different conditions.

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5 Must Know Facts For Your Next Test

  1. Proteomics is the large-scale study of proteomes, typically using techniques like mass spectrometry.
  2. The proteome can change in response to various factors such as environmental conditions and disease states.
  3. Proteomic analysis helps in understanding protein functions, interactions, and cellular processes.
  4. Unlike the genome, which is relatively constant, the proteome is dynamic and fluctuates over time.
  5. Bioinformatics tools are essential for analyzing complex proteomic data.

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