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Polygenic

Written by the Fiveable Content Team • Last updated August 2025
Written by the Fiveable Content Team • Last updated August 2025

Definition

Polygenic describes a trait that is influenced by multiple genes, often located on different chromosomes. Such traits display a range of phenotypes due to the cumulative effect of many alleles.

5 Must Know Facts For Your Next Test

  1. Polygenic traits exhibit continuous variation, like height and skin color.
  2. Genome-wide association studies (GWAS) help identify the multiple genes involved in polygenic traits.
  3. Environmental factors can also influence polygenic traits, adding another layer of complexity.
  4. Polygenic inheritance does not follow simple Mendelian ratios; instead, it shows a bell-curve distribution in populations.
  5. Quantitative Trait Loci (QTL) mapping is a method used to find the specific genetic loci associated with polygenic traits.

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