Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Peripheral resistance is the opposition to blood flow provided by the blood vessels outside of the heart and central circulatory system. It primarily occurs in smaller arteries and arterioles, affecting overall blood pressure and flow rates.
5 Must Know Facts For Your Next Test
Peripheral resistance is influenced by factors such as vessel diameter, blood viscosity, and total vessel length.
An increase in peripheral resistance leads to higher arterial blood pressure.
Vasoconstriction increases peripheral resistance while vasodilation decreases it.
Hormonal signals like adrenaline can affect peripheral resistance by changing vessel diameter.
Peripheral resistance plays a key role in conditions like hypertension (high blood pressure).
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Related terms
Blood Pressure: The force exerted by circulating blood on the walls of the blood vessels.