Written by the Fiveable Content Team • Last updated September 2025
Written by the Fiveable Content Team • Last updated September 2025
Definition
Nucleoplasm is the gel-like substance within the nuclear envelope of eukaryotic cells. It contains the chromosomes and nucleoli and serves as the medium for essential nuclear processes.
5 Must Know Facts For Your Next Test
Nucleoplasm is also known as karyoplasm or nuclear sap.
It provides a suspension medium for the organelles inside the nucleus, including chromatin and nucleolus.
The nucleoplasm contains various enzymes that are essential for DNA replication and RNA transcription.
It plays a crucial role in maintaining the shape and structure of the nucleus.
The composition of nucleoplasm includes water, dissolved ions, and a complex mixture of molecules such as nucleotides and enzymes.
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Related terms
Chromatin: A complex of DNA and protein found in eukaryotic cells that packages long DNA molecules into more compact structures.
Nuclear Envelope: A double membrane that encloses the nucleus in eukaryotic cells, separating it from the cytoplasm.
Nucleolus: A dense structure within the nucleus where ribosomal RNA synthesis occurs.